Improved Visual Acuity and Retinal Integrity with Resveratrol Based Supplementation in Patients with Macular Degeneration

Diyana Ivanova1, Stuart Richer2 and Anish Bhandari3
1Chicago College of Optometry, Midwestern University, Downers Grove, IL, USA
2Captain James A Lovell Federal Health Care Facility, North Chicago, IL, USA
3Rosalind Franklin University of Medicine & Science, Chicago Medical School, North Chicago, IL, USA


These case reports evaluate oral supplementation with a resveratrol based red wine supplement, containing vitamin D3 and labile iron binding inositol hexaphosphate. We appraised function Visual Acuity (VA) and Structure Domain Optical Coherence Tomography (SDOCT) in 3 geriatric patients with atrophic AMD, without clinical alternatives. One female and two males (ages 96, 84, and 85 respectively) were treated under compassionate care guidelines and prescribed Longevinex® (a resveratrol based oral supplement), on a case-by-case-basis. Snellen VA was measured at every visit and photos/SDOCT were also taken to document and track retinal changes. Continual improved VA and retinal integrity were observed. Persistent enhancement is noted on follow up for all patients, continuing for several years for the 96-year-old, thus far. Low dose, low molecular weight nutraceutical molecules can render benefits in the aged with atrophic AMD. Improvement of subjective visual function and retinal integrity is consistent with our previous published reports, as well as reports across several medical disciplines, on the effectiveness of supplementation with a resveratrol-based nutraceutical. This account supports restoration of photoreceptor/RPE function, when other measures have been exhausted by a retinal specialist.

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